Low Price with Good Quality Hot Sale Pharmaceutical Erythromycin CAS 114-07-8
Product Description
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Product Name: Erythromycin
CAS:114-07-8
MF: C37h67no13
EINECS: 204-040-1
Appearance:Powder
Form:White Powder
MW:733.92700
Delivery Time:3-7 Workdays
Type: Synthesis Material Intermediates
Certification:RoHS, BRC, ISO, FDA, HACCP
Shelf Time:2 years,keep away sunlight, keep dry
Shipping Method:FedEx, TNT, DHL, EMS, Eub, Special Line
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Erythromycin estolate, erythromycin propionate lauryl sulfate(Ilosone), is the lauryl sulfate salt of the 2'-propionateester of erythromycin. Erythromycin estolate is acid stableand absorbed as the propionate ester. The ester undergoesslow hydrolysis in vivo. Only the free base binds to bacterialribosomes. Some evidence, however, suggests that theester is taken up by bacterial cells more rapidly than thefree base and undergoes hydrolysis by bacterial esteraseswithin the cells. The incidence of cholestatic hepatitis is reportedlyhigher with the estolate than with other erythromycinpreparations.
Function
1. erythromycin can affect protein synthesis of bacteria, the general effective against gram positive bacteria, mainly used for the treatment of G caused by penicillin resistant Staphylococcus aureus infection.
2. erythromycin is macrolide antibiotics commonly used, antibacterial spectrum similarity with penicillin, mainly used for patients allergic to penicillin, or of penicillin resistant Staphylococcus aureus infection, can also be used for Streptococcus, pneumococcus infection and diphtheria carrier.
3. this is the large ring lactone class antibiotic derivatives intermediates of bacteriostatic antibiotics, antibacterial spectrum was similar to green bacteria.
Application
Erythromycin (Item No. 16486) is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.
Chemical PropertiesWhite or slightly yellow hygroscopic, powder.
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