Top Purity 99.0%Min. Pentagastrin CAS No.: 5534-95-2 API Powder

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: LM- Pentagastrin
• Product Name: Pentagastrin
• CAS: 5534-95-2
• MOQ: 1kg
• Color: White
• Packaging Material: Aluminum Bags+Carton
• Test Method: HPLC
• Certificate: COA/MSDS
• Storage: Cool Dry Area
• Sample: Available
• Payment: Tt, Paypal, Western Union and So on
• Shipping: FedEx, UPS, Specially Line
• Transport Package: 1kg/Kg; 25kg/Drum
• Specification: 98%
• Trademark: Bpanda
• Origin: China
• Production Capacity: Top Purity 99.0%Min. Pentagastrin CAS No.: 5534-95

Product Description

          Top Purity 99.0%Min. Pentagastrin CAS No.: 5534-95-2 API Powder

            

Product Description

 

Product Name:pentagastrin Cas No:5534-95-2 Appearance: white powderCustomized :Customized Shelf Life:2 Years When Properly Stored Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Synonyms:T-BOC-BETA-ALA-TRP-MET-ASP-PHE-NH2;aspartyl]-l-phenylalaninamide;ay6608;boc-beta-ala-try-met-asp-phe(nh2);gastrodiagnost;ici50123;lanineamide;l-methionyl-l-alpha-aspartyl

 

Pentagastrin is a synthetic polypeptide and cholecystokinin-2 (CCK₂) receptor agonist. It binds selectively to CCK₂ receptors in guinea pig brain over CCK₁ receptors in rat pancreas (IC₅₀s = 11 and 1,100 nM, respectively). Pentagastrin increases calcium influx and polyphosphoinositide turnover in rat GH3 pituitary cells (EC₅₀s = 23 and 3.9 nM, respectively). It also increases histidine decarboxylase activity in mucous- and endocrine cell-enriched isolated rabbit fundic mucosal cells (EC₅₀ = 2.9 nM). Pentagastrin induces contraction of isolated pig ileum smooth muscle cells in vitro (EC₅₀ = 30 pM). It increases gastric acid and pepsin secretion in conscious cats in vivo (ED₅₀s = 1.29 and 57.3 nmol/kg² per hour, respectively). Formulations containing pentagastrin have previously been used as a diagnostic aid to evaluate gastric acid secretory function.
Pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid as the pentagastrin-stimulated calcitonin test.

Application

Pentagastrin, also known as pentagastric acid hormone, Peptavlon. It is a synthetic pentapeptide that can promote the secretion of gastric acid, pepsin and internal factors. Its gastric acid secretion effect is equivalent to 1/4 of natural gastrin, but it is stronger than histamine phosphate and diethylpyrazole hydrochloride. It is clinically used for gastric secretory function test and pancreatic function test.

 

 

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