Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Adult |
State: | Powder |
Purity: | >99% |
Samples: |
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Customization: |
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Semaglutide is a medication with a chemical structure similar to the hormone GLP-1. It is designed to improve glycemic control in adults with type 2 diabetes when used alongside diet and exercise.
Semaglutide is the latest GLP-1R agonist approved by the FDA for treating T2DM with a once-weekly injection. It shares similarities with liraglutide but includes two structural modifications. The first is replacing Gly with 2-aminoisobutyric acid (Aib) at position 2. The second is attaching octadecanoic diacid to Lys-26 via a PEG spacer and a γ-glutamic acid linker. These changes make the peptide more DPP-4 resistant than liraglutide, with a high binding affinity for serum albumin, resulting in a 7-day half-life in humans.
(Reference: Lau, Bloch, et al., 2015. Company: Shaanxi Lymall Bpanda Tech Co., Ltd.)
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