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Product Name: Ambroxol CAS: 23828-92-4 MF: C13H19Br2ClN2O MW: 365.4 EINECS: 245-899-2 Appearance:White Powder Form:Powder Type:Pharmaceutical Intermediates Delivery Time:3-7 Workdays Certification:RoHS, BRC, ISO, FDA, HACCP Shelf Time:2 years,keep away sunlight, keep dry Shipping Method:FedEx, TNT, DHL, EMS, Eub, Special Line shelf time |
Ambroxol hydrochloride can increase the secretion of serous fluid in the airway, make the sputum diluted, easy to discharge, so as to improve the respiratory status, so that the respiratory tract mucosal PS can play a normal protective role; At the same time, it also has high pulmonary affinity and can promote the synthesis and secretion of PULMONARY PS, thus maintaining Chemicalbook alveolar stability, which is conducive to the improvement of alveolar function. Therefore, early application of ambroxol hydrochloride can relieve respiratory tract obstruction, improve ventilation, shorten the course of disease, reduce various complications, often used for the treatment of chronic bronchitis aggravation, asthmatic bronchitis, pneumonia, lung abscess and other diseases. Antitussive expectorant, used for acute and chronic respiratory diseases, especially chronic bronchitis expectorant treatment. The active ingredient of ambroxol hydrochloride is bromocyclohexanol, which is a new generation of phlegm dissolving agent and activator of synthesis of pulmonary surfactant. Clinically, it is often used for acute and chronic respiratory diseases accompanied by abnormal sputum secretion and poor sputum function Chemicalbook. Such as acute exacerbation of chronic bronchitis, asthmatic bronchitis, bronchiectasis and tracheal asthma expectorant treatment, the preventive treatment of postoperative pulmonary complications
1. The role of relieving cough and reducing sputum
Ambroxol hydrochloride majorly take effect on the respiratory secretory cells, regulating the secretion of mucous and serous substance, increasing the slurry secretion, degrading the polysaccharide fibers of the acidic glycoprotein in the sputum, inhibiting the synthesis of the acidic protein in the mucous glands and goblet cells, reducing the viscosity of sputum, making the sputum thin and be easy to be discharged; meanwhile, the drug may also increase the frequency of respiratory cilia movement and strength and promote the mucus discharge and respiratory self-purification.
2. Antioxidant effect
Ambroxol hydrochloride has a significant antioxidant effect and can have a significant effect on the reactivity of the free oxygen radicals associated with the lung disease lesions. Studies have shown that ambroxol has strong inhibitory effect on the H2OO2 produced by the neutrophils; in addition, ambroxol can also activate the intracellular glutathione system, promote the biosynthesis of the intracellular glutathione (GSH), thereby causing damaging effects on the oxygen free radicals.