High Purity Inosine CAS 58-63-9 From China Factory

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: LM- Inosine
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Product Name: Inosine
• CAS: 58-63-9
• Grade: Pharmaceutical Grade
• Appearance: White Powder
• Partical Size: 100% Pass 80 Msh
• Test Method: HPLC UV
• Function: Health Care Supplements
• MOQ: 1kg
• Shelf Life: 2 Years
• Certificate: COA/MSDS
• Sample: Available
• Storage: Cool Dry Area
• Payment: Tt, Paypal, Western Union and So on
• Shipping: FedEx, UPS, Specially Line
• Transport Package: 1kg/Bag 25kg/Drum
• Specification: 99%
• Trademark: Bpanda
• Origin: China
• Production Capacity: 5000kg/Year

Product Description

 

       High Purity  Inosine CAS 58-63-9 From China Factory

Product Description

  

Product Name: Inosine CAS:58-63-9  MF:C10H12N4O5 MW:268.226 Appearance:Powder Form:White Powder Delivery Time:3-7 Workdays Melting Point:222-226 °C (dec.)(lit.) Boiling Point:670.5±65.0 °C at 760 mmHg Certification:RoHS, BRC, ISO, FDA, HACCP Shelf Time:2 years,keep away sunlight, keep dry Shipping Method:FedEx, TNT, DHL, EMS, Eub, Special Line shelf time

Inosine, an endogenous purine nucleoside, has immunomodulatory, neuroprotective, and analgesic properties. In vitro: Inosine has been shown to stimulate axonal growth in cell culture and promote corticospinal tract axons to sprout collateral branches after stroke, spinal cord injury and TBI in rodent models.[1] Inosine dose-dependently stimulates cAMP production mediated through the A2AR. Inosine dose-dependently induces A2AR-mediated ERK1/2 phosphorylation.[2] In vivo: The reference for Inosine is 1 or 10 mg/kg, i.p. Preventive treatment with inosine inhibits the development and progression of EAE in C57Bl/6 mice. neuroinflammation and demyelinating processes are blocked by inosine treatment. Additionally, inosine consistently inhibits IL-17 levels in peripheral lymphoid tissue, as well as IL-4 levels and A2AR up-regulation in the spinal cord, likely, through an ERK1-independent pathway. [3] inosine acting through adenosine receptors (ARs) exerts a wide range of anti-inflammatory and immunomodulatory effects in vivo. 

Function

1. Used in the treatment of leucopenia and thrombocytopenia.2. In the treatment of acute hepatitis and chronic hepatitis and liver cirrhosis, hepatic encephalopathy.
3. Used for coronary atherosclerotic heart disease (coronary heart disease), myocardial infarction, rheumatic heart disease,cor pulmonale auxiliary drug use.
4. Used to prevent and mitigate the schistosomiasis prevention drugs caused by the heart and the liver toxicity.
5. Used for eye diseases (central retinal inflammation, optic atrophy) auxiliary drug use.

Specification

Batch No.	HF171121	Quantity	8.5kgs
Mfg. Date	Nov. 21, 2022	Package	As required
Rep. Date	Nov. 25, 2022	Exp. Date	Nov. 20, 2024
Items	Standards		Results
Appearance	White or off-white solid powder		Complies
Identification	By IR		Complies
	By HPLC		Complies
Solubility	Soluble in DMF, sparingly soluble in THF, slightly soluble in meth anol and ace tonitrile, very sightly soluble in ethanol and di chlorome thane, insoluble in water		Complies
Polymorphic Form	Polymorphic form 1		Complies
Melting Point	211ºC~216ºC		212.8ºC~214.9ºC
Water Content	≤ 0.50%		0.10%
Heavy Metals	≤ 20ppm		Complies
Residue on Ignition	≤ 0.20%		0.09%
Related Substance	Any single impurity: ≤0.10%		0.06%
	Total Impurities: ≤1.00%		0.16%
Assay                  (on the anhydrous basis)	98.0%~102.0%		99.94%
Particle Size	D90: ≤100µm		Complies
Reference Standard	In-house Standard
Conclusion	The product complied to In-house standard.
Storage	Preserve in tight,light-resistant containers in a cool place

 

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