| Customization: | Available |
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| Varieties: | Parasite Disease Prevention Medicine |
| Component: | Animal |
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Mebendazole is a broad-spectrum enteroinsecticide, which has been proved by both in vivo and in vitro experiments to directly inhibit the glucose intake of nematodes, resulting in glycogen depletion, making it impossible for nematodes to survive. It has significant effects of killing larvae and inhibiting the development of eggs, but it does not affect the blood glucose level in human body. It can be used to prevent and control intestinal parasitic diseases such as hookworm, roundworm, pinworm, whipworm and fecal nematode.
Mebendazole is thought to work by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells: thereby blocking the uptake of glucose and other nutrients, resulting in the gradual immobilization and eventual death of the helminths. The drug is a highly effective broad spectrum antihelminitic indicated for the treatment of nematode infestations, including round worm, whip worm, thread worm, and hook worm. It is poorly absorbed and has no systemic effects.
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