Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly |
State: | Powder |
Purity: | >98% |
Samples: |
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Customization: |
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P21 is a nootropic peptide targeting improved neurogenesis. In animal studies, P21 has been shown to boost levels of BDNF (brain-derived neurotrophic factor), thus promoting neurogenesis (nerve growth) and inhibiting the formation of Amyloid plaques and Tau proteins seen in Alzheimer's disease.
1.Cell Cycle Regulation: p21 acts as a checkpoint regulator that halts the progression of the cell cycle at the G1 and S phases by inhibiting the activity of CDK-cyclin complexes. This inhibition helps to ensure proper cell cycle progression and prevents uncontrolled cell proliferation.
2.Cell Senescence: p21 is involved in cellular senescence, a state of irreversible growth arrest, by inducing G1 cell cycle arrest. This function is especially important in preventing the replication of damaged DNA and ensuring genomic stability.
3.Tumor Suppression: p21 is recognized as a tumor suppressor protein. Its ability to inhibit cell cycle progression and cell proliferation contributes to preventing the development and progression of tumors.
4.Response to DNA Damage: p21 expression is often induced by DNA damage, and it participates in the DNA damage response pathway by promoting cell cycle arrest and DNA repair.
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