| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Product name: Clobetasol Propionate Appearance:powder Color:White CAS,:25122-46-7 Einecs:246-634-3 M.F.:C25H32CLFO5 M,W,:466.97 Grade: Pharmaceutical grade Purity:99% Sample:Available Storage Condition:Cool Dry Area Shelf Time:2 years,keep away sunlight, keep dry Shipping Method:FedEx, TNT, DHL, EMS, Eub, Special Line |
Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, anti-pruritic, and vasoconstrictive properties. Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, clobetasol propionate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from membrane phospholipids by phospholipase A2.
1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.
2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.
For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.
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