| Customization: | Available |
|---|---|
| Varieties: | Growth Promoting Medicine |
| Component: | Animal |
|
Still deciding? Get samples of US$ 230/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
|
|
Oxolinic acid is a quinolone antibiotic developed in Japan in the 1970s. Dosages 12-20 mg/kg orally administered for five to ten days. The antibiotic works by inhibiting the enzyme DNA gyrase. It also acts as a dopamine reuptake inhibitor and has stimulant effects in mice.
1. The mechanism of action is that it has a wide range of antibacterial activity against gram negative bacteria, but has a weak activity against gram positive bacteria and no activity against fungi.
2.By inhibiting the synthesis of DNA, it prevents bacteria from dividing and multiplying. In the bacterial body, the reverse hypercrimp enzyme is introduced into the hypercrimp structure of DNA.
Oxolinic acid belongs to the first generation of quinolones, and its mechanism of action is to inhibit the synthesis of bacterial deoxynucleotides. It has strong antibacterial effect on gram-negative bacteria, but no antibacterial effect on fungi and mycobacterium tuberculosis. The MIC50 was 0.02 ~ 0.09 g/ml. Carps were given oral infusion of 5mg/kg, 10mg/kg, 20mg/kg and 40mg/kg for a single time. After 15-24h, the blood concentration peaked, and the blood concentration maintained above 0.2 g/ml for 66h. The toxicity of this product is very small, acute toxicity test for carp oral LD50 is more than 4000mg/kg.
){kind=link}