High Purity Sodium Cromoglycate CAS 15826-37-6

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >98%
• Model NO.: LM- Sodium Cromoglycate
• Product Name: Sodium Cromoglycate
• CAS: 15826-37-6
• Einecs No: 239-926-7
• Mf: C23h14o11.2na
• Appearance: White Powder
• Form: Powder
• Package: 1kg/Bag 25kg/Drum
• MOQ: 1kg
• Test Method: HPLC
• Certificate: COA/MSDS
• Sample: Available
• Storage: Cool Dry Area
• Payment: Tt, Paypal, Western Union and So on
• Shipping: FedEx, UPS, Specially Line
• Transport Package: 1kg/Bag 25kg/Drum
• Specification: 98%
• Trademark: Bpanda
• Origin: China

Product Description

 

 High Purity Sodium Cromoglycate CAS 15826-37-6

Product Description

 

Sodium cromoglycate Cromolyn Sodium CAS: 15826-37-6 MF: C23H14O11.2Na MW: 512.33 EINECS: 239-926-7 APIsChemical Properties White Crystalline Powder Usage antiasthmatic, antiallergy Usage Chromone complex which blocks mast cell degranulation

 

Sodium cromoglicate, also known as disodium cromoglicate, has a good preventive and therapeutic effect on immediate allergic reactions. Its mechanism of action is to stabilize the cell membrane of mast cells, prevent mast cells from degranulation, thereby inhibiting the release of allergic reaction mediators such as histamine, serotonin, and slow-reacting substances, thereby inhibiting the adverse effects of allergic reaction mediators on tissues. Its effect of inhibiting the release of allergic reaction mediators may be by inhibiting intracellular cyclic phosphoryl glycoside phosphodiesterase, resulting in an increase in the concentration of intracellular cyclic phosphoryl glycosides (cAMP), preventing calcium ions from being transported into mast cells, thereby stabilizing hypertrophy The cell membrane prevents the release of allergic reaction mediators.
 

Function

1.Sensitive mast cell membrane outside of the calcium channel, preventing calcium influx, inhibition of mast cell degranulation, reducing the release of histamine, slow reactant, leukotrienes and other inflammatory mediators, the role ofspecies selectivity and organ most sensitive to human lung mast cells.

2.Inhibition of sensory nerve endings to release substance P, neurokinin A and B induced tracheal smooth muscle spasm and mucosal edema.

3.Reducing the sensitivity of people with asthma for non-specific stimuli, reducing the attack of bronchospasm.

 

Application

Cromolyn sodium has been used to treat for asthma for many years. It is a derivative of khellin and is proved to be a unique antiallergic agent. The prior administration of cromolyn sodium inhibits allergen-induced histamine release in the animal experiments. Because the oral absorption of cromolyn sodium is minimal and only the powder form of it is available, cromolyn sodium is usually used through being inhaled from a special apparatus. Cromolyn sodium can suppress both immediate and late-onset asthmatic responses and suppress the release of NCF-A. It also inhibits the impairment of mucociliary transport induced by specific bronchial challenge. Moreover, cromolyn sodium also ameliorates exercise-induced asthma .

Specification

 

Test Items	Test Standard
Appearance	White or off-white crystalline powder
Identification	A,B should complies to the standard
Acidity of Alkalinity	Should complies to the standard
Related substance	≤0.5%
Limit of Oxalaet	≤0.35%
Heavy metals	≤20 ppm
Water	≤10.0%
Residual solvents	Ethanol≤0.5%
Assay	98.0%~101.0%

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